As of September 10, 2015, at least 5 live exact matches trademarks were found on USPTO.gov for the term
However, Topsy Turvy is a generic phrase meaning upside down or in a state of complete chaos; this term cannot be trademarked for its dictionary or descriptive meaning.
Please consult with a trademark attorney or expert for information on how this term may be used as a non-profit or in commerce.
This domain could be developed into a fund-raising site for a worthy cause.
On the other hand, Topsy Turvy pretty describes the 2015 political circus taking place in the U.S., so a political site would not be out of the realm of possibility.